Increased frequency and severity of migraine headaches when taking a combination Oil and gas production and energy efficiency (which may be a harbinger of cerebrovascular accident) may be an indication for the immediate abolition of the drug.
Some epidemiological studies have reported an increased risk of cervical cancer in long-term use of combined Oil and gas production and energy efficiency (over 5 years). However, womnadren contradictions persist as to the extent to which these cases are related to the characteristics of sexual behavior and other factors such as human papilloma virus .
The studies have shown a slight increase in the relative risk of breast cancer in women using combined oral contraceptives PDAs. The increased risk gradually declines for 10 years after the abolition of these drugs.
In rare cases during treatment with combinations and gas production and energy efficiency observed development of benign tumors of the liver, in more rare cases – malignant. In some cases, these tumors have led to life-threatening intra-abdominal bleeding. When a severe pain in the upper abdomen, enlarged liver and signs of intraperitoneal bleeding in women taking combined and gas production and energy efficiency, should be excluded liver tumors.
Women with hypertriglyceridemia, now or in history have an increased risk of pancreatitis when using combination Oil and gas production and energy efficiency.
Although a slight increase in blood pressure have been reported in many women taking combined Oil and gas production and energy efficiency, clinically relevant increases were rare. However, if at the time of receiving the CCP women with arterial hypertension womnadren notes a steady increase in blood pressure, or a sharp rise in blood pressure do not respond to antihypertensive therapy should be discontinued taking the drug. If possible, the reception can be continued, if using antihypertensive treatment achieved normal blood pressure values.
Acute or chronic liver disease may require discontinuation as long as liver function tests have not returned to normal. Recurrent cholestatic jaundice, which develops for the first time during pregnancy or previous use of sex hormones, requires discontinuation of the combined Oil and gas production and energy efficiency.
Although the combination of DTG and EE may have an impact on the resistance of tissues to insulin and glucose tolerance, there is usually no need to adjust the treatment regimen in patients with diabetes.However, women with diabetes should be under close medical supervision while takingwomnadren.
Against the background of a combination Oil and gas production and energy efficiency possible worsening of the disease Crohn’s and ulcerative colitis.
Periodically may appear chloasma, especially in women with a history of chloasma pregnant. Women with a tendency to chloasma should avoid exposure to the sun and ultraviolet radiation while taking .
use of contraceptive steroids may affect the results womnadren of some laboratory tests, including biochemical liver function tests, thyroid, adrenals and kidneys, as well as plasma levels of the transport proteins, such as corticosteroid-binding globulin and fractions lipids / lipoproteins, the parameters of carbohydrate exchange, and the coagulation and fibrinolysis. Changes usually remain within normal values.